Abstract: Objective To assess the effect of intravenous low-dose lidocaine infusion on postoperative analgesic and the return of bowel function in patients underwent abdominal cavity surgery. Methods Sixty ASA I~III patients scheduled to undergo abdominal cavity surgery were randomly divided into groups L1、L2 and control group S. In group L1, 1.5 mg∙kg-1 lidocaine was injected during anesthesia induction, then 2 mg∙kg-1∙h-1 IV intraoperatively and 0.5 mg∙kg-1∙h-1 for 48 h postoperatively, in group L2, the same lidocaine application as group L1 except 0.25 mg∙kg-1∙h-1 IV for 48 h postoperatively, in group control, an equal volume of saline were given. Anesthesia was maintained by propofol and remifentanil. Postoperative analgesia was provided by only patient-controlled analgesia with morphine. Blood samples were drawn to measure plasma lidocaine concentrations at the end of surgery, 24 h and 48 h after operations. Postoperative pain was evaluated by visual analog score(VAS) , VAS was measured at rest and during coughing at 2、6、12、24、48 h postoperatively. Summary the consumption of morphine and number of PCA press times, record the times of first flatus and defecation. Results Contrast with the control group, lidocaine reduced remifentanil consumption during surgery as well as postoperative morphine consumption, and shorten times to first flatus and defecation. Corresponding plasma lidocaine concentrations at the end of surgery, 24 h and 48 h after operations were 2.8±1.1μg/ml、1.7±0.7μg/ml、1.5±0.5μg/ml in group L1 and 2.6±1.2μg/ml、1.1±0.4μg/ml、0.9±0.3μg/ml in group L2. Conclusion Intravenous lidocaine improves postoperative analgesia and bowel function recovery after abdominal cavity surgery and reduces opium consumption during surgery.