Objective To compare the effect of iliopsoas plane block (IPB) versus supra‑inguinal fascia iliaca compartment block (S‑FICB) for early analgesia in patients with hip fracture. Methods According to the random number table method, 50 patients with hip fracture were divided into two groups (n=25): an IPB group and a S‑FICB group. Patients in the IPB group were injected with 0.5% ropivacaine at 10 ml between the iliopsoas muscle and the iliofemoral ligament, while those in the S‑FICB group were injected with 0.375% ropivacaine at 30 ml in the supra‑inguinal fascia iliaca compartment. Then, the Visual Analogue Scale (VAS) scores were recorded before nerve block (T0), 10 min after nerve block (T1), 30 min after nerve block (T2), 2 h after nerve block (T3), 4 h after nerve block (T4), 6 h after nerve block (T5) and 12 h after nerve block (T6) and the Manual Muscle Test (MMT) scores at T1 to T6 at resting and with the hip positioned at 15° of flexion were recorded. Their time to onset of nerve block, operation time, patient satisfaction with analgesia, rescue analgesic use and the incidence of adverse reactions were also recorded. Results Compared with those at T0, both groups showed remarkable decreases in VAS scores at T1 to T6 at resting and with the hip positioned at 15° of flexion (all P<0.05). Compared with the S‑FICB group, the IPB group presented significant decreases in VAS scores at T2 to T6 at resting and with the hip positioned at 15° of flexion (all P<0.05), significant increases in MMT scores at T1 to T6 at resting and with the hip positioned at 15° of flexion (all P<0.05), and reductions in the onset time and operation time (P<0.05), with significant improvement in patient satisfaction score with analgesia (P<0.05). There were no adverse reactions related to nerve block or rescue analgesic use in both groups. Conclusions Both IPB and S‑FICB have good analgesic effect on patients with hip fracture. However, IPB shows more effective analgesic effect, which takes less time than S‑FICB, with faster effect and higher patient satisfaction. IPB is a safe and effective method for early analgesia in patients with hip fracture.