国际麻醉学与复苏杂志   2024, Issue (7): 5-5
    
新型冠状病毒感染相关睡眠障碍的发病机制
闫昌昊, 张宗旺1()
1.山东省潍坊医学院麻醉学院
Pathogenesis of sleep disorders associated with SARS‑CoV‑2 infection
 全文:
摘要：

新型冠状病毒感染的全球大流行对人们的健康产生了广泛的影响，与其相关的睡眠问题也普遍存在。新型冠状病毒感染相关睡眠障碍与多种因素相关。文章复习相关文献，对感染新型冠状病毒后的炎症反应、对中枢神经系统的攻击以及神经递质的影响进行了重点阐述，以期待为新型冠状病毒感染相关睡眠障碍的防治提供参考依据。
关键词： 新型冠状病毒感染； 睡眠障碍； 炎症反应； 中枢神经系统； 血脑屏障；
Abstract:

The global pandemic of coronavirus disease 2019 (COVID‑19) has had far‑reaching consequences on public health, and the associated sleep problems are prevalent. Sleep disorders related to COVID‑19 are associated with multiple factors. The article reviews the relevant literature and focuses on the inflammatory response after COVID‑19, the attack of SARS‑CoV‑2 on the central nervous system, and the effect of SARS‑CoV‑2 on neurotransmitters, in an effort to provide evidence for the prevention and treatment of sleep disorders related to SARS‑CoV‑2 infection.
Key words: Coronavirus disease 2019; Sleep disorder; Inflammatory reaction; Central nervous system; Blood brain barrier; Neurotransmitter