Objective:To compare the hemodynamic responses to orotracheal intubation between Airtraq laryngoscope and Macintosh laryngoscope. Methods: 40 patients scheduled for surygery under general anesthesia requiring orotracheal intubation were randomly allocated to undergo intubation using Airtraq (group A,n=20) or Macintosh (group M,n=20) laryngoscope. The following data were recorded and analyzed: glottic exposure time, tracheal intubation time, blood pressure(BP) and heart rate(HR) before and after anesthetic induction, at intubation and thereafter at 1 and 3 minute. The rate pressure product(RPP) at each measuring time point was calculated. Results:There was no significant difference in the glottic exposure time between the two groups，but the intubation time in M group were significantly longer than that in A group．Compared with base value preinduction，BP，HR，and RPP were significantly decreased in both groups．Glottic exposure and tracheal intubation caused significant increases in BP，HR，and RPP as compared with postinduction values．In group M, BP，HR and RPP at 3 min after indubation were significant higher than that with base value preinduction. Conclusion：In comparison to the Macintosh laryngoscope, tracheal intubation with the Airtraq laryngoscope resulted in less alterations in hemodynamic responses.