国际麻醉学与复苏杂志   2011, Issue (2): 0-0
    
术后认知功能障碍的炎症机制
何永涛, 储勤军, 张卫1()
1.郑州大学一附院麻醉科
The possible mechanism of postoperative cognitive dysfunction:inflammation
 全文:
摘要:

术后认知功能障碍(postoperative cognitive dysfunction,POCD)是老年患者手术后常见的中枢神经系统并发症。目前POCD的发病机制尚不清楚。研究表明炎症反应在与衰老有关的认知功能减退中起着重要作用,而手术创伤和应激引起的炎症反应是围术期发生的重要病理生理学改变。近年来炎症反应在POCD发生中的作用备受关注,本文对POCD发生中炎症反应方面的研究进展进行了综述。

关键词: 炎症; 认知功能; 手术
Abstract:

Postoperative cognitive dysfunction (POCD) is a common central nervous system complications in elderly patients. At present the pathogenesis of POCD remains unclear. It is reported that age-related inflammation in cognitive dysfunction plays an important role, and inflammation caused by surgical trauma and stress is an important perioperative pathophysiological change. Recent years ,many people focus on the Inflammation in the POCD. Here make a review with the new development of the research of inflammation in the POCD.

Key words: inflammation ;cognitive dysfunction;operation;