To explore the effect of Intravenous injection of lidocaine during intubation in the elderly patients with type 2 diabetes autonomic nervous system function. Methods: 70 patients undergoing abdominal surgery patients with coronary heart disease, were randomly divided into lidocaine group(group L, n=35, Before induction intravenous 1.5 mg / kg lidocaine) and placebo group (groupP, n=35 Before induction intravenous sodium chloride solution), The changes in HRV were recorded at following time points: prior to anesthesia (T0), 1 min after anesthesia induction (T1) , 3 min after anesthesia induction and prior to intubation (T2), 1 min after intubation(T3), 6min (T4) the heart rate variability (HRPSA) was observed with power spectral analysis. Results: After induction of anesthesia(T1,T2), both groups of total power of HRV spectrum (TP) and low-frequency (LF), high frequency (HF), LF / HF (low frequency / high frequency ratio) were significantly lower than before induction of anesthesia (T0), inter-group comparison group D LF lower than group C; After intubation(T3,T4), two groups of LF, HF and TP were significantly higher than T0 (P <0.05), D group of LF / HF were not significantly higher than T0,however,Cgroup of LF / HF were significantly higher than T0 (P <0.05),inter-group comparison Group D with LF, TP increased significantly lower than the group P (P <0.05), HF inter-group difference was not significant. Conclusion: autonomic nervous system function interferenced following tracheal intubation dur ing induction of anesthesia in elderly patients with type 2 diabetes, Intravenous lidocaine inhibit the intubation operation caused interference on autonomic function. This is beneficial to maintain cardiac autonomic nerve function to old patients with coronary artery disease during intubation.