Abstract: Background Hemorrhagic shock is the primary cause of death in trauma. In emergency treatment of severe patients and the perioperative treatment, fluid resuscitation plays a crucial role. Objective This review summarizes the advances in fluid therapy after refractory hemorrhagic shock. Content In recent years, in addition to the traditional crystalloid solution, many new varieties of solution are used to resuscitate, including sodium pyruvate. And the methods of fluid resuscitation are expanded to intraperitoneal resuscitation from intravenous fluid resuscitation. Trend Sodium pyruvate is a new kind of fluid used for resuscitation in recent studies, and intraperitoneal resuscitation is a new method of resuscitation. New researches have confirmed that they have positive effects in fluid resuscitation. However, the processes, time and curative effect of them still need further research.
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