国际麻醉学与复苏杂志   2014, Issue (1): 0-0
    
右美托咪啶在产科麻醉和镇痛中的应用进展
韩传宝, 周钦海, 蒋秀红, 丁正年1()
1.南京医科大学第一附属医院
Advance in the clinical application of dexmedetomidine in obstetrical anesthesia and analgesia
 全文:
摘要:

背景 右美托咪啶( dexmedetomidine,DEX)是一种高选择性α2受体激动剂,有镇静、镇痛、抗交感等多种药理作用和独特的“清醒镇静”而无呼吸抑制的特点,作为DEX“规定之外(off - lable)”应用之一的在产科中的应用将会越来越多,而且越来越多的研究业已证实DEX在产科麻醉和镇痛的应用具有诸多优势。目的 概述及评价DEX在产科麻醉和镇痛应用中的有效性及安全性,为临床用药提供参考。内容 分析DEX在产科麻醉和镇痛中应用时可能存在的优势。趋向 DEX在产科麻醉和镇痛中应用具有诸多优势,并有更广阔的前景,但需要大样本的临床研究去证实。

关键词: 右美托咪啶;产科;麻醉;镇痛
Abstract:

Background Dexmedetomidine (DEX) is a highly potent selective alpha-2 adrenergic agonis, which has many pharmacological actions,such as sedation, analgesic, anti-sympathetic and so on, and has a unique role as conscious sedation, and without relevant respiratory depression. With off-lable use, and a growing body of studies have proved the advantage of DEX application in obstetric analgesia and anesthesia, the use of DEX in obstetric practice will be more and more.Objective to assess the efficacy and safety of DEX application in obstetric analgesia and anesthesia, and provide evidence for its clinical application. Content to analyze the possible advantage of DEX application in obstetric analgesia and anesthesia. Trend DEX has been proved to possess many advantages in obstetric analgesia and anesthesia, and will be widely used in the future, but still need the future greater sample research to verify.

Key words: Dexmedetomidine; Obstetrics; Anesthesia; Analgesia