国际麻醉学与复苏杂志   2014, Issue (8): 2-2
    
不同浓度甲磺酸罗哌卡因颈丛神经阻滞的临床效果
张宜波, 颜学军, 支利军1()
1.江苏省淮安市楚州医院
Efficacy of different concentration of ropivacaine mesylate in cervical plexus block
 全文:
摘要:

目的 比较不同浓度甲磺酸罗哌卡因实施颈丛神经阻滞的效果。 方法 选择美国麻醉医师协会(ASA)分级Ⅰ~Ⅱ级甲状腺腺瘤患者80例,采用随机数字表法将患者随机分成A、 B、C、D 4组,每组20例,依次采用0.55%、0.45%、0.35%、0.25%甲磺酸罗哌卡因实施颈丛神经阻滞,观察各组患者麻醉后的镇痛效果及呼吸和心率(heart rate, HR)的变化。 结果 A、B、C、D组镇痛效果的平均秩次依次为27、26、26、15, A、B、C组的镇痛效果明显高于D组(P<0.05),A、B、C组之间差异无统计学意义(P>0.05)。A、B、C、D组呼吸困难程度的平均秩次依次为16、38、39、67,A组呼吸困难程度明显高于B、C、D组(P<0.05)。A、B、C、D组HR增加的平均秩次依次为20、39、39、62,A组HR增加明显高于B、C、D组(P<0.05)。 结论 0.35%~0.45%甲磺酸罗哌卡因是颈丛神经阻滞较为合适的局麻药浓度。

关键词: 颈丛; 神经阻滞; 罗哌卡因
Abstract:

Objective To compare the efficacy of different concentration of ropivacaine mesylate in cervical plexus nerve block. Methods Eighty ASAⅠ?蛳Ⅱ thyroid adenoma patients were randomly divided into four groups: group A, group B, group C and group D(n=20), which were respectively performed cervical plexus nerve block with 0.55%, 0.45%, 0.35%, 0.25% Ropivacaine Mesylate. The analgesic effect and changes of breathing rate and heart rate(HR) were observed. Results Compared with group D(15), the mean rank of analgesic effect in group A, group B and group C(27, 26, 26) was significantly higher(P<0.05). The mean rank of difficulty breathing in group B, group C and group D (38, 39, 67) were higher than that in group A(16)(P<0.05). The mean rank of increased HR in group B, group C and group D(39, 39, 62) were higher than that in group A(20)(P<0.05). Conclusions 0.35%?蛳0.45% ropivacaine mesylate is appropriate concentration in cervical plexus nerve block.

Key words: Cervical plexus; Nerve block; Ropivacaine Mesylate