Abstract: Background Resistin-like molecule-α(RELM-α) known as found in inflammatory zone 1(FIZZ1) has been found to be a new type of secretory cytokine in recent years. The studies have showed that RELM-α has many physiological functions and is involved in development of many diseases. Objective To review the physiological actions and mechanism of RELM-α to provide a reference for further research and to inspire new research fields. Content This article is based on the current research progress. RELM-α was summarized mainly from two aspects: the various physiological functions and its mechanism of action. Trend RELM-α has raised more and more researchers' concerns. More studies focus on RELM-α related pulmonary diseases, but less on its roles in other diseases and mechanism of action. So it has a wide research prospect.
|