【Abstnct】Objective To evaluate the clinic effects of controlled hypotension(CH) combined with autogolous(allogeneic) blood transfusion on patients undergoing spinal surgery.Method Forty spinal surgery patients randomly divided into two groups with 20 patients each.The patients with autogolous(allogeneic) blood transfusion in experimental group(n=20)，MAP were maintained in a range of(65±5)mmHg by nitroglycerin.The patients with conventional allogeneic blood transfusion were selected as control group(n=20).Blood transfusion volume，postoperative RBC,Hb,HCT, PLT,PT, APTT, TT as well as transfusion-related complications were compared between two groups. Result The blood loss in experimental group were significantly lower compared with its in control group(P<0.01).The RBC ,Hct ,Hb and PLT in experimental group after the end of operation were lower compared with those before operation.The PT,APTT were increased in experimental group as compared to that before operation.No lung edema,heart failure and unconventionality bleeding occur in two groups.Conclusion CH were safety and decrease blood loss in spinal surgery，Autogolous blood transfusion can reduce the capacity of blood transfusion.