国际麻醉学与复苏杂志   2014, Issue (10): 9-9
    
学龄前儿童先天性脊柱侧凸矫形手术围术期输血的相关因素分析——一项单中心回顾性分析
许华晔, 孙玉娥, 顾小萍, 马正良1()
1.南京医科大学附属鼓楼医院
Clinical research and analysis on perioperative blood transfusion related factors of orthopaedic surgery on preschool children with congenital scoliosis--a single center retrospective analysis
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摘要:

目的 回顾性分析学龄前儿童(≤72个月)行先天性脊柱侧凸矫形手术围术期血液管理的临床特点及相关影响因素。 方法 针对2年以来行先天性脊柱侧凸矫形手术的110例学龄前儿童(≤72个月)相关资料进行回顾性分析,组间比较采用t检验,组内比较采用重复测量的方差分析,多元Logistic回归分析被用来确定异体红细胞输注的独立预测因子。 结果 共有91例患儿(83%)术中输入异体红细胞,与术中异体红细胞输入量存在明显相关性的因素有患儿的体重、术前Cobb角、融合节段、手术时间、截骨数量、失血量以及术前血红蛋白(hemoglobin, Hb)浓度、红细胞比容(hematocrit, Hct)、血小板(blood platelet, Plt)计数,其中独立因素有Cobb角、截骨数量、术前Hb浓度、Hct、Plt计数。输血患儿与未输血患儿比较,术中截骨率、术中出血量和术后24 h伤口引流量显著增加,术后住院时间也明显延长。 结论 可作为围术期输血评估的独立因素有Cobb角、截骨数量、术前Hb浓度、Hct、Plt计数,而与患儿的年龄、体重、融合节段及手术时间无明显相关性,有助于对学龄前儿童先天性脊柱侧凸矫形手术围术期输血需求的早期识别和准确评估,保证患儿的生命安全。

关键词: 先天性脊柱侧凸; 学龄前儿童; 脊柱矫形; 围术期; 输血; 相关因
Abstract:

Objective To retrospectively analyze the clinical characteristics and related factors of perioperative blood management of orthopaedic surgery in preschool children (≤72 months) with congenital scoliosis. Methods One hundred and ten congenital scoliosis surgeries in preschool children(≤72 months) which took place in the last two years in our hospital were enrolled in this retrospective study and the data were analyzed. The t test was used for data analysis between groups, and analysis of variance was repeated for comparison within the group. Multivariate Logistic regression analysis was utilized to identify independent predictors of allogeneic red blood cell transfusion. Results A total of 91 children(83%) were given packed red blood cells transfusion during the operation. The factors which related to the amount of allogeneic red blood cell transfusion included children's body weight, Cobb angle, fusion segments, operative time, bone resection volume, blood loss volume, preoperative Hb, Hct and Plt. The independent factors included cobb angle, bone resection volume, preoperative Hb, Hct, Plt. Compared with the children who were not given blood intraoperatively, intraoperative osteotomy rate, blood loss, 24 h postoperative wound drainage and the length of hospital stay were significantly higher in children who received blood transfusion. Conclusions Cobb angle, bone resection volume, preoperative Hb, Hct, Plt may be the independent perioperative factors for perioperative assessment of blood transfusion. The blood transfusion requirement does not correlate with age, body weight, fusion segment, operative time. These information will help us make early identification and accurate assessment on perioperative blood transfusion requirement in congenital scoliosis surgeries in preschool children.

Key words: Congenital scoliosis; Preschool children; Spine orthosis; Perioperative; Blood transfusion; Related factors analysis