Abstract: Objective To investigate the effects of acupoint electric stimulation on the stress hormone levels during induction and recovery period of general anesthesia in patients with cervical operation. Methods Sixty ASA classⅡ-Ⅲpatients with cervical operation were randomly divided into the treatment group (group T) and the control group (group C) according to the method of random digits table. Bilateral Hegu and Neiguan Great were stimulated continuously 20 min by the Wall KWD-808 type Ⅰ universal pulse electrotherapy instrument before intubation 30 min, and stopped before the end of the operation 30 min in group T. Routine anesthesia without any treatment except for Hegu, Neiguan point electrodes pasting underwent in group. Both groups adopted the same anesthesia. Arterial blood samples were collected respectively at the time of 10 min after delivering into operation room (T0), tracheal intubation (T1), 3 min after intubation (T2), immediately after extubation (T3), 3 min after extubation (T4). Blood samples were centrifuged for 10 min to detect the level of cortisol(COR) and glucose(GLU) in serum. Results There was no significant difference (P>0.05) between two groups in age, weight, operation time, bleeding volume of patients. The COR and the GLU level of T1[(293±80) μg/L,(6.1±1.8) mmol/L,(276±82) μg/L,(5.2±1.0) mmol/L],T2[(298±83) μg/L,(6.3±2.1) mmol/L,(277±84) μg/L,(5.4±0.9) mmol/L],T3[(253±90) μg/L,(5.8±1.7) mmol/L,(239±89) μg/L,(5.6±1.5) mmol/L],T4[(275±79) μg/L,(6.2±1.8) mmol/L,(263±80) μg/L,(5.7±1.4) mmol/L]were always higher than T0[(211±54) μg/L,(4.9±0.8) mmol/L,(206±56)μg/L,(4.7±0.7) mmol/L](P<0.05) within groups. The COR and GLU levels of patients in T1[(293±80) μg/L,(6.1±1.8) mmol/L],T2 [(298±83) μg/L,(6.3±2.1) mmol/L],T3[(253±90) μg/L,(5.8±1.7) mmol/L],T4[(275±79) μg/L,(6.2±1.8) mmol/L] in group C were higher than the same time in group T(P<0.05). Conclusions Acupoint electric stimulation applied to patients with cervical operation, can significantly reduce the stress effect during induction and recovery of anesthesia, and has a significance in clinical application.
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