国际麻醉学与复苏杂志   2015, Issue (4): 9-9
    
四种方法预测困难气道的Meta分析
顾青, 李怡然, 姜虹1()
1.上海交通大学医学院附属第九人民医院
The Meta analysis of four methods in predicting difficult airway
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摘要:

目的 通过Meta分析评价改良Mallampati分级(modified Mallampati classification, MMP)、上唇咬合试验(upper lip bite test, ULBT)、甲颏间距(thyromental distance, TMD)、上下切牙间距(interincisor gap, IIG)预测困难气道的准确性。 方法 收集2003年1月~2013年12月国内外公开发表的,以气道声门暴露分级(Cormack and Lehnane, CL)3~4级和/或困难气管插管记分量表(intubation difficulty scale, IDS)>5和/或临床操作为金标准的,关于MMP、ULBT、TMD、IIG预测困难气道的中英文文献。采用STATA12.0、Meta-Disc1.4软件检验异质性,根据异质性结果选择相应效应模型,计算汇总灵敏度、汇总特异度,以综合受试者工作特性曲线(summary receiver operating characteristic curves, SROC)、曲线下面积(area under the curve, AUC)评价诊断方法的准确性。 结果 25篇文献符合纳入标准,其中ULBT的诊断比值比(diagnostic odds ratio, DOR)值最高为19.83(9.29~42.31),它的AUC和Q*分别为0.900 4和0.831 6。 结论 对于困难气道,在这4种方法中,上唇咬合试验是一种预测困难气道准确性较高的方法,并且具有较强的判别能力。

关键词: 困难气道; 预测因素; Meta分析; Mallampati分级; 上唇咬合试验
Abstract:

Objective To assess the accuracy of predicting difficult airway by Meta analysis of the modified Mallampati classification(MMP), the upper lip bite test (ULBT), thyromental distance (TMD), interincisor gap(IIG). Methods The Cormack and Lehnane's grading(CL)3-4 and (or) intubation difficulty scale(IDS)>5 were taken as golden standards for diagnosis of difficult airway. Articles of predicting difficult airway by MMP, ULBT, TMD, and IIG published in English or Chinese from Jan 2003-Dec 2013 were collected. The sensitivity, specificity, summary receiver operating characteristic curves (SROC), area under the curve(AUC) and the heterogeneity were calculated with software of Meta-DiSc 1.4 and STATA 12.0. Results Twenty-five articles were got into the standard. The diagnostic odds ratio (DOR) of ULBT was 19.83(9.29-42.31). The AUC and Q* of ULBT were 0.900 4 and 0.831 6 respectively. Conclusions Among MMP,ULBT,TMD, and IIG, the ULBT is a higher accuracy predictive method for detecting and judging difficult airway.

Key words: Difficult airway; Predictive factor; Meta analysis; Modified Mallampati classification; Upper lip bite test; Thyromental distance; Interincisor gap