Background labor pain, a kind of strongly physical and mental feeling，is one of the leading course for the high rate of cesarean delivery in china currently. Objective This article is present the progress of remifentanil in labor pain. Content Nowadays, remifentanil is taken seriously gradually for its own advantage and become a new choose to labor analgesic except for the gold standard: epidural blockade. There have many researches certified that remifentanil patient-controlled intravenous analgesia is safe and effective for the pregnant and have no side effect to fetal / newborn. Trend The administration model and dose of remifentanil PCIA is a research hot pot recently.