【Objective】To observe the effects of forgetfulness analgesia slow induction combined Glidescope video laryngoscope in patients with obstructive sleep apnea syndrome(OSAS). 【Methods】Sixty ASAⅠ～Ⅱ patients aging 27～48 years and weighing 78～106kg undergoing uvulopalatopharyngoplasty surgery （UPPP）were randomly assigned for A,B 2 groups. Group A were nasotracheal intubation with Glidescope video laryngoscope after forgetfulness analgesia slow induction and Group B were nasotracheal intubation with Macintosh direct laryngoscope after fast induction. In all subjects, the relatively stable depth of anesthesia was maintained by propofol and remifentanil, the muscular relaxant was Rocuronium. The MAP, HR and SPO2 were recorded before anesthesia induction(T0), intubation(T1), at the time of intubation(T2) and 3min after intubation(T3). Cormark-Lehane grade, the oppression of laryngeal external, the auxiliary of Magil intubating forceps, the incidence of blood on the laryngoscope and the conditions of intubation were all recorded. Compare the anesthesia recovery and untoward effect of the two groups. 【Results】Compare with T0, group A had stable vital signs in the process of anesthesia induction and intubation, but the MAP and HR of group B were decreased in T1 and increased to varying degrees in T2 、T3(P＜0.05). The glottis exposure of group A is better than that of group B, group A had shorter intubation time, higher success rate of intubation for the first time. The oppression of laryngeal external, auxiliary of Magil intubating forceps and analgesic dose were less than group B(P＜0.05). Compare with group A, the anesthesia recovery time and extubation time of group B were extended, but the Sedation-Agitation Scale and VAS score were higher. 【Conclusion】 Forgetfulness analgesia slow induction combined Glidescope video laryngoscope in OSAS patients undergoing UPPP surgery, not only make intubation method simple and rapid, but also make the hemodynamic of anesthetic induction period and intraoperative more smoothly. After operating, quickly complete awakening, satisfactory analgesia and fewer postoperative agitation all make it well be used in anesthesia in patients with obstructive sleep apnea syndrome.