Abstract: Abstract: Objective To discuss the effects of multimodal analgesia combined with flurbiprofen and compatibility of dexamethasone on postoperative recovery after gynecological laparoscopic day-case surgery. Method 90 cases of patients undergoing elective gynecological laparoscopic day-case surgery were randomly divided into 3 groups,during anaesthetic induction:group A and B was given 0.1mg/kg dexamethasone by intravenous injection, but group C was given 2 ml normal saline by intravenous injection; after anaesthetic induction: group A and C was given 1mg/kg flurbiprofen plus 0.9% NaCl 100 ml by intravenous injection slowly, but group B was given normal saline by intravenous injection slowly. All groups were given 8 mg ondansetron by intravenous injection at the end of surgery. The postoperative pain of the patients at 0、2、4、6 and 8h after surgery in 3 groups,was evaluated and recorded using a visual analogue scale(VAS)and bruggrmann comfort scale(BCS).Other related adverse effects were also noted. Results VAS scores at 0, 2h after surgery was significantly lower in group A than in group C(P<0.05), group C was significantly lower than group B(P<0.05); VAS scores at 4h after surgery was significantly lower in group A and C than in group B(P<0.05); BCS scores at 0, 2h after surgery was significantly higher in group A than in group C(P<0.05), group C was significantly higher than group B(P<0.05); BCS scores at 4h after surgery was significantly higher in group A and C than in group B (P<0.05). Compared to group A(0%) and C(10%), the incidence of using postoperative analgesic drugs was significantly higher in group B(23%)(P<0.05); the incidence of postoperative nausea and vomiting (PONV)were significantly higher in group B(27%)and C(30%) than that in group A(3%)(P<0.05); the incidence of extending stay time were significantly higher in group B(23%)and C(20%)than that in group A(3%) (P<0.05).Conclusion Multimodal analgesia combined with flurbiprofen and compatibility of dexamethasone can significantly improve the comfort degree of patients after gynecologic laparoscopic day-csae surgery.
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