Objective To investigate whether the incidences of umbilical blood gas abnormalities are different between preeclampsia parturient and healthy parturient following goal-directed fluid therapy. Methods Twenty six stable preeclampsia parturient and twenty six healthy parturient scheduled for elective cesarean section were recruited. Standard combined spinal epidural anesthesia was performed with low dose bupivacaine (7.5mg). At the timepoint of spinal injection, goal-directed fluid therapy was employed to optimize the stroke volume via the ΔSV provided by LiDCOrapid system. The umbilical blood gas abnormalities were recorded and analyzed. Results The ratio of parturient who needed second fluid challenge was higher in the preeclampsia group compared with the healthy control (54% vs 32% ).There were no significant differences in the maternal hypotension incidence and vasopressors used. In healthy parturient, the oxygen saturations in both umbilical artery and vein were significantly higher, and level of lactic acid were lower than that in the pre-eclampsia group (p < 0.05) .Conclusions Except for oxygen saturations and lactic acid, there was no significant difference in other umbilical blood gas parameters between stable preeclampsia parturient and healthy parturient following goal-directed fluid therapy in cesarean section.