【Abstract】 Objective To explore the feasibility of the Fast-Track Anesthesia in the Enhanced Recovery After Surgery of Colorectal carcinoma. Methods 104 colorectal carcinoma patients which were randomly divided into the conventional control group (52 cases) and the enhanced recovery group(52 cases) were analyzed in the study . Results The heart rate and the fluctuation of blood pressure in the enhanced recovery group were more stable than those of the conventional control group. Besides, the general anesthetics in the enhanced recovery group was significantly less than that in the conventional control group (Propofolum 286.5±26.4mg VS 286.5±26.4mg; Vecuronium 13.6±2.5mg VS 15.8±2.3mg), and the recovery time（13.5±3.5min VS 26.4±12.8min）, the time of anus exhaust(26.4±12.8h VS 53.6±18.5h), the length of hospital stay(5.6±1.3d VS 8±2.6d ) and the incidence of pulmonary infection(3.85% VS 9.62%) in the patients were less than those in the control group(P<0.05）. Conclusion The Fast-Track Anesthesia was performed through the entire perioperative period, and played an important role in the Enhanced Recovery After Surgery of Colorectal carcinoma.