ObjectiveTo compared with double cavity bronchial catheter, the bronchial occluder in thoracoscopy pulmonary bulla surgery efficacy and safety of application. MethodsSelect January 2014 - March 2014 in our hospital, a total of 80 patients with pulmonary bulla as the research object. Patients were randomly divided into two groups, one group with double cavity bronchial tube, another group of the bronchial occluder, compare the situation of general information, intubation in two groups of patients, blood gas analysis in different time and the occurrence of adverse reactions. Results The results of the surgical field score less than group A, group B A intubation success rate higher than that of group A, and were P < 0.05, the difference is statistically significant; PaO2 single cavity ventilation after two group were lower than after anesthesia and recovery after double cavity ventilation, and 60 min after single cavity ventilation is lower than the single cavity ventilation after 10 min, and in group A single cavity ventilation PaO2 lower than group B, P < 0.05, the difference is statistically significant; Two groups of PaCO2 there was no statistically significant difference in each period of time (P > 0.05); Two groups in A single cavity ventilation Ppeal and Pplat are higher, but the group A Ppeal and Pplat in single cavity ventilation were higher than group B, P < 0.05, the difference is statistically significant; A group of patients in 11 cases of patients with hoarseness and sore throat, the incidence was 27.5%, and group B (3 cases), rate of 7.5%, two groups of comparisons X2 = 6.24, P < 0.05, the difference is statistically significant. ConclusionBronchial occluder thoracoscopy pulmonary bulla on surgery to remove the good field of vision, small in blood gas changes, and postoperative discomfort is lighter, is an effective safe way, worth clinical promotion.