Background　Perioperative transfusion in patients with malignant is a major problem in clinical practice. In recent years, numerous studies have shown that perioperative transfusion lead to immune suppression, recurrence and metastasis, which reduced the survival rate. Therefore, clinicians paid more attention to transfusion therapy and tumor-related issues.　Objective　Raising awareness of reasonable perioperative transfusion for the patients with malignant tumor, further implementation of rational use of blood.　Content　Progress of perioperative transfusion in patients with malignant tumor.　Trend　Perioperative transfusion for patients with malignant tumor should be based on the evaluation about the risk-benefit ratio. We should emphasize the rational use of blood, use a variety means of blood protection method, reduce the unnecessary transfusions. And so we can improve long-term prognosis of patients with malignant tumor.