国际麻醉学与复苏杂志   2017, Issue (7): 6-6
    
针刺调节缺血性脑血管病围手术期脑血流量和脑神经功能的研究进展
赵春美, 安立新, 谢思宁1()
1.首都医科大学附属北京天坛医院
Research advance of the adjustment effect of acupuncture on the preoperative and postoperative cerebral blood flow and brain function of ischemic cerebrovascular disease
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摘要:

背景 针刺成为卒中后康复治疗的重要辅助措施之一。 目的 综述针刺治疗脑卒中的临床进展及其调节机制。 内容 针刺可明显改善卒中后抑郁(post-stroke depression, PSD)状态,促进偏瘫恢复,降低痉挛状态的发生率,促进认知功能的恢复。此外,针刺可预防颈动脉内膜剥脱术(carotid endarterectomy, CEA)及血管内支架置入术(carotid artery stenting, CAS)术后的再灌注综合征。针刺通过多种机制改善卒中后状态:改善脑缺血局部微循环,拮抗氧自由基损伤,控制炎症反应,减少血栓形成,调节信号转导通路及蛋白质,促进侧支循环等。 趋向 针刺对脑卒中的治疗效果肯定,其可通过多种途径调节卒中后脑神经功能状态。但将针刺应用于脑卒中手术术中的效果仍需进一步研究。

关键词: 脑卒中; 针刺; 脑血流量; 脑神经功能
Abstract:

Background Acupuncture becomes one of the important auxiliary treatments for the rehabilitation of stroke patients. Objective This article reviews recent progress in mechanisms underlying the treatment of stroke with acupuncture. Content In stroke patients, acupuncture can significantly improve post-stroke depression(PSD), promote recovery from hemiplegia, reduce incidence of spasticity, and restores cognitive function. Additionally, acupuncture may help to prevent the reperfusion syndrome after carotid endarterectomy(CEA) and carotid artery stenting(CAS). Physiologically, acupuncture improves local microcirculation in ischemic region, reduces damage of oxygen-free radicals, controls inflammation, prevents formation of thrombosis, regulates several signal transduction pathways, and promotes reconstruction of collateral circulation. These physiological properties may contribute to the therapeutic benefits of acupuncture in stroke. Trend Acupuncture has evident therapeutic values in stroke: improving the functional recovery in various aspects. Further studies are required to elucidate the clinical benefits of acupuncture to brain ischemia patients receiving CEA or CAS.

Key words: Stroke; Acupuncture; Cerebral blood flow; Brain function