Ｏｂｊｅｃｔｉｖｅ　Systematic review the effect of propofol versus sevoflurane for corrected QT(QTc).　Methods　The PubMed, Embase, Cochrane Library, CNKI and VIP databases were searched to obtain studies concerning the effect of sevoflurane versus propofol on cardiac cardiac electrophysiology. The quality of studies were assessed in accordance with the Cochrane Handbook for Systematic Reviews of Interventions. After data extraction, Meta-analysis was performed with RevMan software 5.0.　Results　Three hundred and thirteen patients were involved in seven randomized-controlled trials (RCT) were used. The result of Meta-analysis shows that compared with myocardium repolarization time in propofol group, the duration of myocardium repolarize in sevoflurane group was prolonged obviously [(weighted mean difference, WMD)=－23.53, 95%CI(－30.57－ －16.49)](P＜0.01), but the parameters of HR[(WMD=0.22, 95%CI(－4.92－5.36)] and MAP[(WMD=－2.23, 95%CI(－8.66－4.20)] are not significantly different(P＞0.05).　Conclusions　Compared with propofol, sevoflurane prolong the duration of myocardium repolarization, increase the risk of arrhythmia, but the parameters of haemodynamics between two groups showed no significant differences. The result demonstrated that in the process of anesthesia induction, the effects of propofol on cardiac electrophysiology is less and safer than sevoflurane.