Ｏｂｊｅｃｔｉｖｅ　To explore the effect of oxygen supply tracheal intubation on ventilation quality in patients under general anesthesia.　Methods　Sixty patients for great saphenous vein closures with laser under general anesthesia were randomly divided into two groups (each including 30 cases) and respectively received tracheal intubation with either size 7 common tracheal tubes (group C) or oxygen supply tracheal tubes with the same size (group O). During operation, HR, MAP, SpO2, Ppeak, Ppla and PETCO2 were monitored and recorded. All patients were admitted to anesthesia recovery room after surgery. When patients regained autonomous respiration, the PETCO2, the number of patents relying on continue oxygen supply and the number of patents with reduced SpO2 during aspiration of sputum were recorded.　Results　There was no significant difference in HR and MAP between two groups in operation room before and during operation (P＞0.05). Group C and group O did not differ in Ppeak, Ppla and PETCO2 during operation (P＞0.05). However, there was significant difference in postoperative HR, MAP and PETCO2 between the two groups (P<0.05). Additionally, the number of patients in group C depending on continued oxygen supply was significantly higher than that in group O (P<0.05).　Conclusions　Oxygen supply tracheal tubes were able to ensure ventilation and oxygen supply during and after the surgery, and reduce the dependence of patients on auxiliary breathing equipment during anesthesia recovery.