Objective To evaluate the clinical effects of the intelligent patient-control analgesia pump for labor analgesia and its influence on mother and fetus. Methods 120 primiparas were randomly divided into two groups, intelligent patient-control analgesia pump group(Group I,n=60) and traditional patient-control analgesia pump group (Group T, n=60). All of them received epidural analgesia, and the analgesic solution was 0.1% ropivacaine plus 0.5μg/ml sufentanil. Both groups received an initial bolus of 12ml analgesic solution, and the basic pump settings for the two groups were 5ml/h, 5ml, 15min (basal infusion rate, bolus dose and lock time) . Furthermore, the advanced settings in the group I were as follows: if the parturient required 0 bolus demand in the previous hour, the basal infusion rate was decreased by 5ml/h automatically; if the parturient required 1 or 2 bolus demands in the previous hour, the basal infusion rate was maintained; if the parturient required more than 2 bolus demands in the previous hour, the basal infusion rate was increased by 5ml/h automatically; and the max permissible analgesic solution volume was limited to 30ml per hour. The pump was ended at the end of the second stage of labor. The follow outcome measures, including the usage of analgesics, the number of breakthrough pain, the VAS scores, the Modified Bromage score, the duration of labor, delivery mode, neonate condition, side-effects as well as the maternal satisfaction, were recorded. Results Finally, we analyzed 113 parturient (57 in group I and 56 in group T). Compared with group T, in the group I, the VAS score at full cervical dilatation and the incidence of breakthrough pain were significantly decreased (P < 0.05); meanwhile, the basal infusion rate at the second stage of labor force delivery and the maternal satisfaction were significantly increased (P < 0.05) without prolonged process of the second stage of labor; and no significant differences were found in the usage of analgesics, the duration of labor, delivery mode, the neonate condition as well as the side-effects. Conclusion The intelligent patient-control analgesia pump is effective for labor analgesia. It provides lower incidence of breakthrough pain and higher maternal satisfaction. the dosage of analgesics and side-effects do not increase.The intelligent patient-control analgesia pump is safe for mother and fetus．