Ｏｂｊｅｃｔｉｖｅ　To study the analgesic effect of different doses of flurbiprofen axetil on post-cesarean analgesia with butorphanol.　Methods　Three hundreds patients undergoing elective cesarean section were randomly allocated into three group by random number table (n=100). After fetus delivery, three groups were all received patient controlled intravenous analgesia (PCIA) with butorphanol 12 mg diluted by normal saline (NS) into 100 ml (background infusion 2 ml/h, patient control analgesia (PCA) 2 ml, lockout interval 15 min). After the baby was removed, 50 mg and 100 mg flurbiprofen axetil were slowly injected intravenously in group Ⅱ and group Ⅲ, respectively. The Visual Analogue Scale(VAS) scores of incision pain, Ramesay sedation score, total PCA times and the degree of satisfaction about post-operative analgesia were measured at 4, 8, 12 h and 24 h after surgery respectively. Weight of lochia 6 h after surgery and the time of milk secretion were recorded. Other side effects such as hypoxemia, nausea, vomiting including neonatal complications were also recorded.　Results　There were no statistical differences in demographics among three groups. The data of all patients were collected and no patient needed extra analgesia. Compared with group Ⅰ, the VAS scores and the consumption of butorphanol of 4, 8, 12, 24 h were lower in the group Ⅱ and group Ⅲ, while the degree of satisfaction was higher(P<0.05). Compared with group Ⅱ, VAS score and the consumption of butorphanol of 4, 8 h were lower in the group Ⅲ, and the satisfaction degree was higher (P<0.05). There were no statistical differences in weight of lochia, the time of milk secretion, or side effects like hypoxemia, nausea, vomiting after surgeries(P>0.05). There were no statistical differences in Ramsay sedation scores (P>0.05).　Conclusions　Flurbiprofen axetil could provide better analgesic effect on post-cesarean analgesia with butorphanol (100 mg was superior to 50 mg). Furthermore, it did not influence uterine contraction or the time of milk secretion.