国际麻醉学与复苏杂志   2020, Issue (5): 0-0
    
手术患者肺保护性通气策略:国际专家组推荐规范的解读
薄禄龙, 卞金俊, 邓小明1()
1.上海长海医院
Lung‑protective ventilation for the surgical patient: an interpretation of international expert panel‑based consensus recommendations
 全文:
摘要:

术后肺部并发症(postoperative pulmonary complications, PPCs)是影响外科患者围手术期康复和预后的重要原因。越来越多的证据表明,术中使用肺保护性通气策略可减少PPCs。首个针对手术患者肺保护性通气策略的国际专家组推荐规范于2019年发布,其中有22项建议和4项声明。通过解读该推荐规范的重点内容,文章将更新术中通气策略的最新观点。内容包括:患者术前评估应包括肺部风险的专项评估;个体化机械通气可改善术中呼吸功能,预防PPCs;呼吸机的初始潮气量应设置为6~8 ml/kg(预测体重),呼气末正压至少为5 cmH2O(1 cmH2O=0.098 kPa);在实施肺复张策略时,应予以最低有效的驱动压和最少次数的有效复张。未来应通过进一步的临床研究以明确肺保护性通气策略对以患者为中心的预后结局的影响。

关键词: 麻醉; 指南; 术后肺部并发症; 肺保护性通气; 呼气末正压; 肺复张
Abstract:

Postoperative pulmonary complications (PPCs) are the important causes that affect the perioperative rehabilitation and prognosis of surgical patients. Increasing evidence suggests that reduction of PPCs can be accomplished by using lung‑protective ventilation strategies intraoperatively. In 2019, international expert panel‑based consensus recommendations on lung‑protective ventilation for the surgical patient were released, with twenty‑two recommendations and four statements. In the current review, the key content of the consensus recommendations will be interpreted, so as to update ventilation strategies during surgery. A dedicated score should be used for preoperative pulmonary risk evaluation, and an individualised mechanical ventilation may improve the mechanics of breathing and respiratory function, and prevent PPCs. The ventilator should initially be set to a tidal volume of 6‒8 ml/kg (predicted body weight) and the positive end‑expiratory pressure should be at least 5 cmH2O (1 cmH2O=0.098 kPa). When lung recruitment manoeuvres are performed, the lowest effective pressure and shortest effective time or fewest number of breaths should be used. Further clinical studies are warranted to further confirm the effects of lung‑protective ventilation strategies on patient‑centered outcomes.

Key words: Anesthesia; Guideline; Postoperative pulmonary complications; Lung‑protective ventilation; Positive end‑expiratory pressure; Recruitment manoeuvres