国际麻醉学与复苏杂志   2021, Issue (8): 15-15
    
小儿术后谵妄临床研究进展
王玉慧, 温超, 金锦花, 薛富善1()
1.中国医学科学院整形外科医院
Clinical research advances in pediatric postoperative delirium
 全文:
摘要:

术后谵妄(postoperative delirium, POD)是小儿术后常见的神经认知并发症,可降低患儿术后恢复质量,增加家庭和社会负担,但目前尚未出现防治小儿POD的循证指南。文章对近年来小儿POD相关危险因素、诊断和干预措施等方面的临床研究进行综述,旨在加强小儿围手术期管理,降低小儿POD风险,改善患儿预后。年龄、术前焦虑和疼痛是小儿POD的重要预测因子,缓解患儿术前焦虑是预防的关键,儿童麻醉苏醒期谵妄评分(Paediatric Anaesthesia Emergence Delirium, PAED)是最常用且经过验证的小儿POD评价量表。目前尚不能确定有效防治POD的最佳药物,有待采用统一神经精神量表开展大样本多中心研究。

关键词: 小儿; 认知功能; 预测因子; 麻醉; 谵妄
Abstract:

Postoperative delirium (POD) is a common postoperative neurocognitive complication in pediatric patients that can affect the recovery quality of children, which adds a burden to the family and society. However, currently, there is no specific evidence‑based guideline for pediatric POD. This review summarized the clinical advances in pediatric POD in terms of risk factors, diagnosis, and intervention aims to strengthen perioperative management, reduce the risk of POD, and improve the prognosis of children. Age, preoperative anxiety, and pain are essential predictors of POD in children. Alleviating preoperative anxiety is a critical factor in preventing POD. Pediatric Anaesthesia Emergence Delirium (PAED) is the most commonly used and validated scale for identifying pediatric POD. Up to now, it is not clear which drug is the best agent for preventing POD. To further understand POD in children, it is necessary to perform multi‑center studies with large‑scale enrollment using a unified neuropsychiatric scale.

Key words: Children; Cognitive function; Predict factor; Anesthesia; Delirium