Objective To compare the effectiveness and safety of Baska laryngeal mask airway (BLMA) with Advance laryngeal mask airway (ALMA) in ambulatory breast surgery. Methods According to the random number table method, 68 patients, aged 18‒64 years, American Society of Anesthesiologists (ASA) grade Ⅰ or Ⅱ, who underwent ambulatory breast surgery were divided into two groups (n=34): ALMA group (group A) and BLMA group (group B). Both groups were compared for insertion time, first‑attempt success rate, the number of placement, oropharyngeal leak pressure, hemodynamic variables, complications of laryngeal mask placement and 24 h postoperative complications. Results Compared with group A, group B presented decreases in the first insertion time and intraoperative laryngeal mask leakage rate, and higher oropharyngeal leak pressure immediately and 30 min after laryngeal mask insertion (P<0.05). Group B showed a lower first‑attempt success rate and a higher second‑attempt success rate than group A (P<0.05). Two patients in group A were unsuccessful in laryngeal mask inserting and changed to tracheal intubation. There was no significant difference in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate between the two groups at each time point (P>0.05). Compared with group A, group B showed decreases in the incidence of painful swallowing (mild), blood in the mask, and reflux (P<0.05), and there was no significant difference in the incidence of complications 24 h after surgery (P>0.05). Conclusions BLMA is easier to be placed, and offers a higher oropharyngeal leak pressure with less reflux, and less damage to the oropharynx than ALMA, which can be safely and effectively used for airway management in ambulatory breast surgery.