临床广泛将自由氧疗（liberal oxygen therapy, LOT）作为重症患者救治的辅助治疗。但高浓度给氧治疗的过度医疗干预可破坏机体生理平衡，甚至导致严重并发症。降低医源性并发症与病死率是近年来为进一步提高健康水平及疾病治愈率的新需求。文章分析近几年相关研究动态，阐述保守氧疗（conservative oxygen therapy, COT）在临床中的作用及其与相关疾病近远期并发症、病死率的关系，为提高氧疗效果，减少相关并发症，提供临床与理论依据。
Liberal oxygen therapy (LOT) is widely used as adjuvant therapy in the treatment of critically ill patients. However, excessive medical intervention in the treatment of high-concentration hyperoxia can destroy the physiological balance of the body and even lead to serious complications. Reducing iatrogenic complications and mortality is a new demand in recent years to further improve health levels and cure rates. This paper analyzes the relevant research in recent years, and expounds on the clinical role of conservative oxygen therapy (COT) and its relationship with the near and long-term complications and mortality of related diseases, to provide a clinical and theoretical basis for improving the effect of oxygen therapy and reducing the related complications.
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