国际麻醉学与复苏杂志   2023, Issue (10): 4-4
    
静脉淤血在心脏手术相关急性肾损伤中的研究进展
胡兰鑫, 葛亚力1()
1.南京医科大学附属南京医院(南京市第一医院)
Progress of venous congestion in acute kidney injury associated with cardiac surgery
 全文:
摘要:

心脏手术相关的急性肾损伤(cardiac surgery-associated acute kidney injury,CSA-AKI)是心脏手术后的主要并发症之一,其对患者的近期和远期生存率都有负面影响。早前,心脏相关的急性肾损伤主要与低血压有关,肾脏的低灌注被认为是导致肾脏血流量(renal blood flow,RBF)和肾小球滤过率(GFR)降低的主要原因;但近几年的研究发现静脉淤血在心脏病人身上很常见,静脉淤血在肾脏生理和病理生理学中的作用越来越受到重视。有研究显示,心脏疾病患者静脉淤血与肾功能损伤和病死率相关,用中心静脉压(CVP)作为静脉淤血的量化指标,认为高CVP是被确定为心脏手术相关急性肾损伤的独立危险因素。以下综述将讨论静脉淤血与心脏手术相关急性肾损伤的研究进展。

关键词: 急性肾损伤;心脏手术;静脉淤血
Abstract:

cardiac surgery-associated acute kidney injury (CSA-AKI) is one of the major complications after cardiac surgery, which has a negative impact on both short-term and long-term survival. Previously, heart-related acute kidney injury was primarily associated with hypotension, and renal hypoperfusion was thought to be the primary cause of decreased renal blood flow (RBF) and glomerular filtration rate (GFR), leading to AKI; However, recent studies have found that venous congestion is very common in cardiac patients, so the role of venous congestion in renal physiology and pathophysiology has been paid more and more attention. Some studies have shown that venous congestion in patients with heart disease is associated with renal function injury and mortality. Central venous pressure (CVP) is used as a quantitative indicator of venous congestion, and high CVP is considered to be an independent risk factor for cardiac surgery-related acute kidney injury. The following review will discuss the research progress of venous congestion and cardiac surgery-related acute kidney injury.

Key words: Acute kidney injury ; cardiac surgery ; venous congestion