国际麻醉学与复苏杂志   2023, Issue (9): 3-3
    
衰弱对老年非心脏手术患者术后转归影响的研究进展
赵月凯, 王秀丽1()
1.河北医科大学第三医院麻醉科
Research advances on the effect of frailty on postoperative outcomes in elderly patients undergoing non‑cardiac surgery
 全文:
摘要:

衰弱是一种涉及多个生理系统功能储备损害或丧失的临床综合征,其特征为对外部压力源的脆弱性增加,维持稳态能力变差,导致不良后果的风险增加,已被证实与术后不良结局有关。文章旨在阐述衰弱的发病机制、评估方法、老年术前衰弱对术后转归的影响及衰弱干预措施,为制定围手术期个体化管理方案,改善患者预后提供临床指导。

关键词: 衰弱; 老年人; 术后并发症; 术前评估; 干预方式
Abstract:

Frailty is a clinical syndrome involving damage to or loss of functional reserves of multiple physiological systems, characterized by increased vulnerability to external stressors and poor ability to maintain homeostasis, leading to an increased risk of adverse outcomes, which has been shown to be associated with adverse postoperative outcomes. This review aims to expound on the pathogenesis, evaluation methods of frailty, the influence of preoperative frailty on postoperative outcomes in elderly people, and frail intervention measures, so as to provide clinical guidance for developing individualized management plans in the perioperative period and improving the prognosis of patients.

Key words: Frailty; Aged; Postoperative complication; Preoperative evaluation; Intervention modalities