国际麻醉学与复苏杂志   2010, Issue (3): 270-273
    
超前镇痛的相关研究进展
刘晓芬 胡宪文 李云 张野1()
1.230601合肥，安徽医科大学第二附属医院麻醉科（刘晓芬、 胡宪文、李云、 张野）
Effects of parecoxib and morphine on postoperative hyperalgesia after remifentanil-based anesthesia in orthopedics patients
 全文:
摘要：

超前镇痛是通过防止外周和中枢敏化来降低伤害性刺激引起的痛觉过敏和痛觉异常的一种镇痛方法。现介绍超 前镇痛的机制、 临床常用方法及药物， 并展望超前镇痛亟待解决的问题。
关键词： 超前镇痛；镇痛机制；临床应用
Abstract:

Preemptive analgesia is one of the analgesia measures which decreases the incidence of hyperalgesia and allodynia by reducing peripheral and central sensitization. Current knowledge of the mechanism of preemptive analgesia, clinical application and drugs are summarized in this review, as well as controversy on preemptive analgesia.
Key words: Preemptive analgesia；Analgesia mechanism；Clinical application