[ABSTRACT] Background Blood supply to organs low or blocked can result in ischaemic injury,and the role of IL-17 in Organs Ischaemic Injury had increasingly reported recent years. Objective To provide theoretic basis for clinical and basic research by reviewing the recent advances of IL-17 in Organs Ischaemic Injury. Content In this article，IL-17 cytokine family, gene regulation of IL-17, signaling pathway will be reviewed,and the recent advances of IL-17 in Organs Ischaemic Injury will be emphasized. Trend According to the effect targets of IL-17 participating in the process of Organs Ischemic Injury, Some drugs or therapies may be able to reduce or reverse Organs Ischemic Injury, and they will be the new focus of clinical and basic research.