背景 近红外光是指在700 nm~1 300 nm范围内，介于光和中红外光之间的电磁波。 目的 现对近红外光有关检测脑氧饱和度和脑血流动力学，进而监测大脑活动的有关原理作一综述。 内容 近红外光能穿透生物组织数厘米，在近红外光范围内，组织吸收近红外光的主要粒子是含有金属的色基；引起光在颅内衰减的主要物质是氧合血红蛋白（oxyhemoglobin， HbO2），还原血红蛋白（deoxygenated hemoglobin， Hb）和细胞色素aa3；根据其吸收光谱的不同，可计算出局部脑氧饱和度。 趋向 利用近红外光谱技术（near infrared spectroscopy， NIRS）检测脑氧饱和度已成为医学研究的热点领域，将成为临床医学上极具发展潜力的分析和研究技术手段。
Background Near infrared light， in the range of 700 nm to 1 300 nm， is the electromagnetic wave between light and infrared light. Objective To review the use of near infrared light monitoring cerebral saturation and cerebral hemodynamics， and the mechanism of monitoring cerebral activities. Content The near infrared light can penetrate several centimeters of the biological tissue. In the range of near infrared light， the main particle that absorbs near infrared light is the metal-containing color base. And the main substances causing intracranial light attenuation are oxyhemoglobin（HbO2）， deoxygenated hemoglobin（Hb） and cytochrome aa3. The regional cerebral saturation could be calculated according to the difference of their absorption spectrum. Trend Using of near infrared spectroscopy（NIRS） monitoring cerebral saturation is a newly trend in medical research， which would become a means of analysis and research with great development potential in clinical medicine.
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