Abstract: 【Abstract】 Background The mechanism of myocardial ischemia reperfusion connect with peroxidation, calcium overload, mitochondria injury, myocardial cells apoptosis and so on. Recently the sdudy indicate that the gap junctional intercellular communication of myocardial cells are be concerned with myocardial ischemia reperfusion injury. Objective This article summarized the relationship of the gap junctional connexin 43 of myocardial cells with myocardial ischemia reperfusion injury. Content Connexin 43 could be protected myocardial during myocardial ischemia reperfusion injury. The mechanism may be related with calcium overload, mitochondria injury, myocardial cells apoptosis and so on. Trend Researches in future should be taken to further explore of the relation between Cx43 and apoptosis, and strengthen the cilinial applications.
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