Advance in anesthesia and Intraocular pressure 【Abstract】Background perioperative increased pressure within the eye can cause serious eye complications, resulting in visual field defects or even blindness. Studies have shown that, the perioperative procedures and anesthetic can lead to intraocular pressure changes, affecting the blood supply of the eye. Purposes contemplated systematic exposition of perioperative physiological and anesthetic commonly used drugs on intraocular pressure affect the status quo and progress, to provide a reference for clinical work, and inspire new research ideas. Summary of the contents of intraocular pressure during anesthesia factors affect the physiological and drug. Tend to be seen from the recent study, perioperative physiology and the effects of drugs on intraocular pressure mechanism, the researchers conducted a more in-depth discussion.