[Abstract] Objective To observe the clinical effect of subcoracoid blockage of brachial plexus using nerve stimulator. Methods 60 patients (ASA I-II) scheduled for upper extremity surgery were divided into two groups randomly: subcoracoid group(group A) and armpit group (group B). Group A inserted insulative needle of nerve stimulator perpendicularly to the skin at subcoracoid 2cm. Group B inserted the needle at the site of most intense pulse of axillary artery. The initial current was set to be 1mA and the frequency was 2Hz. In group A, when the current was lower to 0.5mA, the muscle twitch of median, ulnar and radial nerve innervating distriction still can be seen, 0.5% levobupivacaine 10ml was injected differently. Group B just injected the same local anesthetics 30ml at one site. The onset and durative time of anesthesia were recorded. The clinical effect, the achievement ratio and the degree of satisfaction were compared as well. Results The onset time of anesthesia of group A was shorter than that of group B (P<0.05). There was no significant difference of both groups in the durative time of anesthesia. The achievement ratio in group A was 93.3-100%, which was significant higher than that of group B (P<0.05). The side effect in two groups were similar. Conclusion Subcoracoid blockage of brachial plexus using nerve stimulator is easily to perform, which has shorter onset time of anesthesia and higher achievement ratio.