国际麻醉学与复苏杂志   2014, Issue (10): 2-2
    
功能近红外光谱成像技术在认知功能评估中的应用
胡天然, 于布为1()
1.上海交通大学医学院附属瑞金医院麻醉科
The application of functional near infrared spectroscopy in cognitive neuroscience
 全文:
摘要:

背景 功能近红外光谱技术(functional near infrared spectroscopy, fNIRS)是一种安全无创的脑功能成像手段,具有较高的时间分辨率。该技术通过多部位测量大脑皮层氧合血红蛋白和去氧血红蛋白的变化,了解各脑区功能状态下局部血流动力学的改变,比较不同认知任务下皮层功能变化的差异。 目的 探讨不同认知任务下各脑区氧合状态的变化及其意义。 内容 对fNIRS的基本原理及其在认知科学领域的应用作一综述。 趋向 fNIRS将为全身麻醉机制、麻醉药对神经功能以及认知发育的影响等研究提供重要参考价值。

关键词: 功能近红外光谱技术; 光学层析成像; 皮层映射成像; 脑功能成像;
Abstract:

Background Functional near infrared spectroscopy (fNIRS) is a non-invasive brain mapping technique with high temporal resolution. Optical topography, based on fNIRS technique, can display the hemodynamic changes of cerebral cortex under different cognition load through multi-site measurement of oxygenated and deoxygenated hemoglobin variations. Objective It is discussed that the changes of oxygenation status in different cerebral cortex under various cognitive tasks. Content The basic principle of fNIRS and its application in neurocognitive studies are reviewed. Trend fNIRS is of great reference value for future studies in the mechanisms of general anesthesia and impacts of the impact of anesthetics on on neurological function and cognitive development.

Key words: Functional near infrared spectroscopy; Optical topography; Cortical mapping; Functional brain imaging; Cognition