Abstract: Objective To observe the effect of low dose dexmedetomidine on emergence agitation after tonsillectomy and/or adenoidectomy in children with sevoflurane anesthesia. Methods Ninety children, aged 2 y-8 y, ASAⅠ-Ⅱ, undergoing adenotonsillectomy and/or Adenoidectomy, were randomly divided into two groups: the dexmedetomidine group(D group, n=45) and the saline group(S group, n=45). Anesthesia was maintained with sevoflurane and oxygen. D group patients were given dexmedetomidine 0.3 μg/kg (in 10 min) and maintained with 0.2 μg·kg-1·h-1. The S group was given the same dosage saline. Intraoperative hemodynamics were recorded every 5 min. Time of spontaneous breathing, time of extubation, and the emergence agitation in PACU were recorded. Results The incidence of emergence agitation was 28.89% in group D, and 64.44 % in group S, the mean agitation scores in the D group were lower than the S group except at 10 min. Conclusions So low dose dexmedetomidine could reduce the emergence agitation in children receiving sevoflurane undergoing tonsillectomy and/or adenoidectomy.
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