国际麻醉学与复苏杂志   2015, Issue (1): 1-1
    
回收式自体输血与异体输血对机体炎症反应的影响
徐消寒, 张卫1()
1.郑州大学第一附属医院麻醉科
Postoperative inflammatory response of autologous blood transfusion and allogeneic blood transfusion
 全文:
摘要:

背景 自体血回输在围术期应用日益广泛。自体血和异体血输注均会对机体的炎症反应产生一定的影响。 目的 对两种输血方式后机体炎症因子的变化进行对比,阐述围术期两种输血方式对患者的影响。 内容 异体血在输注过程中产生大量炎症因子,如白细胞介素(interleukin, IL)-2、IL-6、IL-8、IL-10、肿瘤坏死因子-α(tumor necrosis factor-α, TNF-α)等,引起机体炎症反应,可能是术后并发症的重要原因。自体血在回收、过滤的过程中同样会产生一定量的炎症因子。 趋向 对骨科自体血及异体血应用进行对比,研究两种输血方式对机体炎症反应的影响。

关键词: 自体血回输; 异体血; 炎症因子
Abstract:

Backgroud Autologous blood transfusion is widely used during the perioperative period. Both autologous blood and allogeneic blood transfusion affects the patient inflammatory response. Objective To compare the changes on the inflammatory factors after the two ways of transfusion and elaborate the impacts on the perioperative patients using the two kinds of transfusion techniques. Content Large amounts of inflammatory cytokines such as interleukin(IL)-2, IL-6, IL-8, IL-10, tumor necrosis factor-α(TNF-α), etc. They are produced caused by the system′s inflammatory response during the allogeneic blood transfusion,may cause postoperative complications. Certain amounts of inflammatory cytokines are also produced during the process of recycling and filtering the autologous blood. Trend Compare and study the impacts on the system′s inflammatory response using the two ways of transfusion techniques in the orthopedics surgeries.

Key words: Autologous transfusion; Allogeneic blood transfusion; Inflammatory cytokines