Ｏｂｊｅｃｔｉｖｅ　To compare the efficacy and safety of laryngeal mask airway Supreme （SLMA） and laryngeal mask airway ProSeal（PLMA） in paediatric patients undergoing general anesthesia.　Methods　Sixty ASAⅠ-Ⅱchildren undergoing surgery with general anesthesia， 9 months to 5 years of age and 10 kg-20 kg in weight， were randomly divided into two groups（n=30）， SLMA group（group S） and PLMA group（group P）. 0.1 mg/kg midazolam， 0.01 mg/kg atropine， 2 mg/kg propofol， 2 μg/kg fentanyl and 0.6 mg/kg of rocuronium were used for induction of anesthesia. Insertion time， success rate of first insertion difficulty of airway device placement， oropharyngeal leak pressure（OLP）， difficulty of gastric access and fiberoptic determination of laryngeal mask airway（LMA） position were compared. Heart rate， mean arterial pressure were measured when inserting the LMA. Inspiratory tidal volume， expired tidal volume， peak airway pressure and compliance were recorded during the surgery. The postoperative complications were also compared.　Results　The OLP was lower in group S than that in group P［（19.7±2.2） cmH2O vs （22.3±3.4） cmH2O］（P<0.05）（1 cmH2O=0.098 kPa）. There was no siginificant difference in insertion time， success rate of first insertion， difficulty of airway device placement， fiberoptic assessment， difficulty of gastric access and complications between two groups.　Conclusions　PLMA has a higher OLP and provides better sealing to the airway. Both of them can be efficacily used in pediatric general anesthesia.