This report described the emergency treatment process of intratracheal tumor hemorrhage caused by endotracheal intubation under induction of general anesthesia in 2 patients without preoperative airway obstruction. Fibreoptic bronchoscopy is the best choice for diagnosis of intratracheal tumor. Blocking the lower trachea off by inflating the cuff of endotracheal tube and sucking out the trachea hemorrhage timely with trendelenburg position can reduce aspirated blood effectively and improve oxygen supply and ventilation.