Objective To moninter the perioperative clinical index and prognosis of congenital heart disease with severe pulmonary hypertension in patients with cesarean section. Methods Congenital heart disease with severe pulmonary hypertension in pregnant women, spinal anesthesia for cesarean section break. Age ranged from 19 to 38 y, weight 55 ~ 74 kg, pregnancy 35 ~ 39 W, pulmonary artery pressure 80 ~110 mmHg. NYHA: 1 cases in grade IV, 5 cases in grade III, 2 cases of grade II, none of them underwent heart operation. Among 5 cases in premature infants, 3 cases were full-term infants. The relatively clinic hemodynamics data during operations were observed. Results Perioperative patients with relatively stable hemodynamics, anaesthesia effect is satisfactory. All 8 patients survived, 7 cases of patients with stable hemodynamics. In patients with suspected cardiac insufficiency of 1 case, after the positive strong heart diuresis treatment patient gradually smooth, two days after the slow withdrawal. Conclusion For congenital heart disease with severe pulmonary hypertension patients with cesarean section, select the intrathecal block combined with good block lever control and moderate preload before anesthesia helps to maintain stable hemodynamics. But for NYHA greater than grade IV patients the methods of anesthesia remains to be discussed.