国际麻醉学与复苏杂志   2018, Issue (1): 0-0
    
呼出气一氧化氮在慢性阻塞性肺疾病及全身麻醉肺保护中应用进展
李立纲, 安妲, 王东春, 李恩有1()
1.哈尔滨医科大学第一临床医学院
Advance in application of exhaled nitric oxide in patients with chronic obstructive pulmonary disease and lung protection in general anesthesia
 全文:
摘要：

背景　呼出气一氧化氮（fractional exhaled nitric oxide, FeNO）测定在指导哮喘诊断及治疗方面的重要地位已经得到公认，而FeNO与慢性阻塞性肺疾病（chronic obstructive pulmonary disease, COPD）之间的关系尚不明确。　目的　探讨FeNO与COPD及其相关并发症之间的相关性。　内容　综述FeNO产生机制及其在COPD及相关并发症中扮演的角色，阐述FeNO监测在全身麻醉中的应用。　趋向　寻求可以早期诊断COPD的方法及潜在生物标记物，预警全身麻醉术后肺部并发症的发生。
关键词： 呼出气；　一氧化氮；　慢性阻塞性肺疾病
Abstract:

Background　Measurement of fractional exhaled nitric oxide(FeNO) plays an important role in the diagnosis and treatment guidelines for asthma has been confirmed, however, the relationship between FeNO and chronic obstructive pulmonary disease(COPD) is not clear.　Objective　To explore the correlation between FeNO and COPD and its related complications.　Contents　Giving a summary of the mechanism of FeNO production and its role in COPD and related complications; describing the application of FeNO monitoring in general anesthesia.　Trends　To get a method or a potential biomarker for early diagnosis of COPD; Obtaining early warning of pulmonary complications after general anesthesia.
Key words: Exhaled；　Nitric Oxide；　Chronic obstructive pulmonary disease