Abstract: Objective To explore the effect of intraoperative blood salvage on indexes of erythrocyte in orthopedic surgery of diabetic patients.Methods A total of 70 patients undergoing selective orthopaedics surgery were included in this study.They were divided into 7 groups with 10 patients each.Non-diabetes served as control (Group D).The others were divided into 6 groups according to the diabetes history and the level of hemoglobin A1c (HbA1c). 0 to 5-year diabetics whose HbA1c level lower than 7% were incorporated into Group A1,while those whose HbA1c level above 7% belong to group A2,6 to 10-year diabetics were assigned into Group B1 ( HbA1c level less than 7% ) and B2 (more than 7% ).More than 10 years diabetics were incorporated into Group C1 ( HbA1c level less than 7% ) and C2 (more than 7% ).The amount of bleeding,blood salvage and erythrocyte recovery rates were compared among the seven groups.5ml blood samples were drawn at three time points,including preoperation(T0),after blood collection (T1) and washing (T2),and then blood gas analysis and erythrocyte related index were tested.Results The red blood cell recovery of group B2 (55.2±4.9) % and C2 (52.9±2.7) % dpressed as compared with control(60.1±5.3)% (P<0.05). At T0,the erythrocyte mean corpuscular volume of group B2,C1 and C2 rised compared with group D,and goup C2 was higher than group A1(P<0.05).The red blood cell distribution width in group A2,B2,C1 and C2 was evidently broadened than group D at T0 and T1.And group B2 and C2 showed increased width compared with group A1(P<0.05).The level of pH and Na+ of each group increased quite significantly at T1 and T2 as compared with T0(P<0.05).The K+ concentration of each group rised significant at T1 and reduced below the level of T0 at T2(P<0.05). There was no difference among all the erythrocyte related index, pH,Na+ and K+ at T2. Conclusions The recovery rates of erythrocyte in diabetic patients those whose HbA1c were poorly controlled were declined.But the salvaged blood could be retransfused safely.
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