国际麻醉学与复苏杂志   2018, Issue (4): 0-0
    
Barbotage注射法和单次注射法应用于腰麻剖宫产的比较
汪愫洁, 景宇淼, 徐铭军1()
1.首都医科大学附属北京妇产医院
Comparison of Barbotage and Single injection Applied to Spinal anesthesia in Cesarean section
 全文:
摘要:

目的 比较Barbotage(Bbt)注射法和单次注射法应用于腰麻剖宫产时,产生的感觉及运动阻滞效果,产妇血流动力学的变化,新生儿Apgar评分等。 方法 100例20-40岁,ASAⅡ级,足月产妇于L2-3行CSEA剖宫产手术,随机分为2组(B组和S组),每组50例,两组腰麻剂量均为0.5%罗哌卡因2.2mL(11mg)。B组采用Bbt注射法,即向产妇蛛网膜下隙注入半量局麻药1.1mL后,回抽脑脊液至2.1mL,并再次推入1.1mL混合液;第二次回抽达1.6mL,继续推入1.1mL混合液;第三次回抽1.1mL后,将残余液体全部推注完毕——该法共推注4次,每次均为1.1mL,总注药时长为44s,平均速率为0.1mL/s。S组采用单次注射法(Single),2.2ml药液一次推入蛛网膜下隙,注药总时长22s,给药速度同前组。腰麻后,若产妇出现血压降低,使用多巴胺或去氧肾上腺素维持循环稳定。分别记录其入室基础血压、注药后4min、6min、8min、10min,共5个时点(t0, t1-4)的血压、心率、相对感觉阻滞平面、运动阻滞评分、使用血管活性药物及硬膜外追加用药的情况,观察并记录围术期不良事件的发生,以及新生儿情况。 结果 在t1-t4,B组感觉平面上升速度快于S组;t4时,B组最大感觉阻滞平面高于S组(P<0.05);两组在t1-t4的改良Bromage评分差异无统计学意义(P>0.05);去氧肾上腺素在S组的使用率高于B组(P<0.05);B、S两组硬膜外追加局麻药量、新生儿Apgar评分,均未见统计学差异(P>0.05)。 结论 在腰麻剖宫产术中,Bbt注射法起效较快,药物扩散广,阻滞平面较单次注射法高,同时循环相对稳定。

关键词: Barbotage法;罗哌卡因;注射速度;腰麻;剖宫产
Abstract:

OBJECTIVE Compare the outcome of barbotage and sigle injection applied to spinal anesthesia in cesarean section, include sensation blockeffect, motor block effect, changes of maternal hemodynamics, neonatal Apgar scores. METHOD One hundred ASAⅡparturients of 20-40 years with full-term pregnancy were scheduled for cesarean delivery under L2-3 CSEA were included. They were randomly divided into 2 groups with 50 cases each. 0.5% Ropivacaine 2.2mL(11mg) were used in all patients. A barbotage technique was carried out in group B: 1st step, inject 1.1mL from 2.2mL total solution and withdrawing back to 2.1mL; 2nd step, inject 1.1mL from 2.1mL solution and withdrawing back to 1.6mL; 3rd step, inject 1.1mL from 1.6mL solution and withdrawing back to 1.1mL; 4th step, inject the rest solution into subarachnoid space. The total injection time of group B is 44s with an average speed of 0.1mL/s. Single injection is carried out in group S within 22s and average speed of 0.1mL/s. Use dopamine and phenylephrine to stabilize maternal circle system, and top up local anesthetics if needed. Record maternal blood pressure, heart rate, level of sensory block, Bromage score, usage of vasoactive drugs and local anesthetics at time of resting and 4min, 6min, 8min, 10min after injection. Record perioperative adverse reaction and condition of newborns. RESULT The rate of block sensory level rise: B>S(P<0.05); within t4, the highest sensory block level: B>S(P<0.05); the usage rate of phenylephrine: B0.05). CONCLUSION In the spinal anesthesia of cesarean section, Barbotage provides wider distribution of local anesthetics in subarachnoid space, which lead to faster nerve block and higher block level, with more stable blood pressure and heart rate.

Key words: Barbotage(Bbt);Ropivacaine;Injection speed;spinal anesthesia;Cesarean section