Abstract: Objective To observe the effects of one time erector spinae plane block (ESPB) combined with patient controlled intravenous analgesia(PCIA) on postoperative pain and satisfactory extent of patients undergoing radical resection of esophageal carcinoma by thoracotomy operation. Methods Forty patients[20 males and 20 females, American Society of Anesthesiologists(ASA) status Ⅰ or Ⅱ], scheduled for radical resection of esophageal carcinoma by open chest surgery, were randomly assigned into two groups: ESPB combined with PCIA group(group EP) and PCIA only group (group IA). ESPB was performed in group EP before anesthesia induction. The effect was evaluated by detecting the area of block after 20 min. The patients in both group used PCIA after surgery. Visual Analogue Scale (VAS) scores were recorded at 1, 6, 12, 24 h and 48 h after operation both in the resting and the coughing state. The times of pressing analgesic pump, the total volume of analgesic drugs infused by analgesic pump, the frequency and extent of adverse reaction and satisfactory extent of patients were recorded as well. Results Twenty min after EPSB, pain sense of patients in group EP was successfully blocked in the skin area innervated by spinal nerve between T3 to T9。The VAS scores both at rest and during coughing in group EP were lower than those in group IA(P<0.05). The times of pressing analgesic pump and the volume of infused analgesic drugs were significantly less in group EP than the times and volume in group IA (P<0.05). Meanwhile, the frequencies of nausea and vomiting in group EP were significantly lower than those in group IA (P<0.05). Also, the degree of satisfaction in group EP was significantly higher than the degree in group IA(P<0.05). Conclusions For radical resection of esophageal carcinoma by thoracotomy, ESPB combined with PCIA is a more effective method for postoperative analgesia than PCIA only. Also, the gross satisfactory extent is significantly higher in group EP than that in group IA. Less adverse effects were observed in patients of group EP.
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