Based on traditional blind puncture used in epidural anesthesia, a new pressure waveform monitoring method has been proposed to evaluate the success of epidural anesthesia in recent years. Compared with the commonly used epidural anesthesia puncture methods, such as the loss‑of‑resistance technique and other new techniques, for example, ultrasonography, computed tomography, and interventional angiography, a large number of studies have shown that the pressure waveform is an objective indicator of epidural anesthesia. Pressure‑waveform method can timely monitor the epidural anesthesia process. It is safe, reliable, simple and practical. This article reviews the principle of the pressure waveform in the application of epidural anesthesia and summarizes the characteristics of the pressure waveform and its clinical application during the puncture and catheterization of the epidural anesthesia. The pressure waveform provides a simple auxiliary method for epidural anesthesia, which can distinguish the true positive and false positive of resistance of loss.