Sugammadsx sodium injection is a new antagonist against non‑depolarizing muscle relaxants. It can quickly, safely and controllably antagonize the neuromuscular blockage of steroidal muscle relaxants such as rocuronium. Compared with traditional muscle antagonists like anticholinesterase, it is highly antagonistic to nerve muscle blockage, without effects on the cholinergic system, and may be widely used in the recovery period after anesthesia. The current review focuses on the following aspect of sugammadsx: mechanism of action, efficacy, its use in special patients, neuromuscular block residual and re‑arrow poisoning, and adverse reactions, so as to provide evidence for rational use and improve the quality of recovery after anesthesia.